Difference between revisions of "Serous borderline tumour"
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'''Serous borderline tumour''' is a Muellerian epithelial [[ovarian tumour]] with a behaviour that borders on [[malignant]]. | '''Serous borderline tumour''' is a Muellerian epithelial [[ovarian tumour]] with a behaviour that borders on [[malignant]]. | ||
It is also known as '''serous ovarian tumour of low malignant potential'' | It is also known as '''serous tumour of low malignant potential''', abbreviated ''SLMP''.<ref name=pmid10836293>{{Cite journal | last1 = Seidman | first1 = JD. | last2 = Kurman | first2 = RJ. | title = Ovarian serous borderline tumors: a critical review of the literature with emphasis on prognostic indicators. | journal = Hum Pathol | volume = 31 | issue = 5 | pages = 539-57 | month = May | year = 2000 | doi = | PMID = 10836293 }}</ref><ref name=pmid10881733>{{Cite journal | last1 = Dietel | first1 = M. | last2 = Hauptmann | first2 = S. | title = Serous tumors of low malignant potential of the ovary. 1. Diagnostic pathology. | journal = Virchows Arch | volume = 436 | issue = 5 | pages = 403-12 | month = May | year = 2000 | doi = | PMID = 10881733 }}</ref> | ||
''Serous ovarian tumour of low malignant potential'' redirects here.<ref name=pmid10881733/> | |||
==General== | ==General== | ||
Revision as of 02:10, 29 March 2016
Serous borderline tumour is a Muellerian epithelial ovarian tumour with a behaviour that borders on malignant.
It is also known as serous tumour of low malignant potential, abbreviated SLMP.[1][2]
Serous ovarian tumour of low malignant potential redirects here.[2]
General
- Usually benign.
- Require long term follow-up.
Microscopic
Features:[3]
- Cuboidal to columnar epithelium with mild to moderate atypia.
- No invasive.
- "Sparse" mitoses.
- +/-Psammoma bodies.
- +/-Micropapillary architecture - often described as a medusa head pattern.
DDx:
- Serous carcinoma of the ovary - focus a with stromal invasion >5mm (linear measurement) or > 10 mm2 (area).[3]
- Invasive cells are "pink", i.e. have abundant eosinophilic cytoplasm,[3]; also, cells usu. large (~2-3x size of non-invasive component), and typically have an enlarged nucleus (~2x non-invasive component).
- Clear cell carcinoma of the ovary - classically associated with endometriosis, have simpler, smaller papillae without branching.
Images:
Subclassification
Typical subdivided into:[5]
- Micropapillary serous borderline tumour.
- Typical serous borderline tumour (SBOT).
Sign out
Cyst and Right Fallopian Tube, Excision:
- SEROUS BORDERLINE TUMOUR with micropapillary architecture, see comment.
- Fallopian tube within normal limits.
- NEGATIVE for evidence of invasion.
Comment:
The lesion appears to be confined to a cystic structure.
See also
References
- ↑ Seidman, JD.; Kurman, RJ. (May 2000). "Ovarian serous borderline tumors: a critical review of the literature with emphasis on prognostic indicators.". Hum Pathol 31 (5): 539-57. PMID 10836293.
- ↑ 2.0 2.1 Dietel, M.; Hauptmann, S. (May 2000). "Serous tumors of low malignant potential of the ovary. 1. Diagnostic pathology.". Virchows Arch 436 (5): 403-12. PMID 10881733.
- ↑ 3.0 3.1 3.2 Nucci, Marisa R.; Oliva, Esther (2009). Gynecologic Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 399. ISBN 978-0443069208.
- ↑ Burkholz, KJ.; Wood, BP.; Zuppan, C.. "Best cases from the AFIP: Borderline papillary serous tumor of the right ovary.". Radiographics 25 (6): 1689-92. doi:10.1148/rg.256055015. PMID 16284143.
- ↑ Park, JY.; Kim, DY.; Kim, JH.; Kim, YM.; Kim, KR.; Kim, YT.; Nam, JH. (Dec 2011). "Micropapillary pattern in serous borderline ovarian tumors: does it matter?". Gynecol Oncol 123 (3): 511-6. doi:10.1016/j.ygyno.2011.08.008. PMID 21917305.