Difference between revisions of "Paired box gene 8"
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{{ Infobox immunostain | {{ Infobox immunostain | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Poorly differentiated carcinoma -- PAX8 - intermed mag.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = PAX8 staining in a poorly differentiated [[carcinoma]]. | ||
| Abbrev = PAX8 | | Abbrev = PAX8 | ||
| Synonyms = | | Synonyms = | ||
Revision as of 22:23, 1 August 2016
| Paired box gene 8 | |
|---|---|
| Immunostain in short | |
 PAX8 staining in a poorly differentiated carcinoma. | |
| Abbreviation | PAX8 |
| Use | RCC versus other, gynecologic tract malignancy versus other |
| Subspeciality | gynecologic pathology, genitourinary pathology |
| Positive | renal cell carcinomas, renal oncocytoma, thyroid tumours, serous carcinoma, endometrial carcinomas |
Paired box gene 8, commonly known by the abbreviation PAX8, is a commonly used immunostain in gynecologic pathology and genitourinary pathology.
Tumours with positive staining
- Thyroid tumours ~ 90%.[1]
- Renal cell carcinomas ~ 90%.[1]
- Renal oncocytomas ~ 80%.[1]
- High-grade ovarian serous carcinomas ~ 99%.[1]
- Nonserous epithelial ovarian neoplasms ~ 70%.[1]
- Endometrial carcinomas ~ 98%.[1]