Difference between revisions of "Low-grade oncocytic renal tumour"
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*Tubular or solid architecture. | *Tubular or solid architecture. | ||
*Edematous areas with loosly arranged cells. | *Edematous areas with loosly arranged cells. | ||
DDx: | |||
*[[Renal oncocytoma]]. | |||
*[[Chromophobe renal cell carcinoma]]. | |||
*[[Hybrid/oncocytic tumour]]. | |||
==IHC== | ==IHC== | ||
Revision as of 18:13, 20 March 2018
Renal oncocytic tumour that are CD117 negative and CK7 positive is unusual renal tumour that does not neatly fit into any WHO renal neoplasia category.
General
- Very rare.
Microscopic
Features:[1]
- Oncocytic cytoplasm.
- Round nuclei.
- Tubular or solid architecture.
- Edematous areas with loosly arranged cells.
DDx:
IHC
Features:
- CD10 -ve/+ve.
- AMACR -ve/+ve.
- CA9 -ve.
- CK20 -ve.
See also
References
- ↑ Trpkov K, Williamson S, Martinek P, Cheng L, San Miguel Fraile P, Yilmaz A, Hes O, Oncocytic Renal Tumors with CD117 Negative, Cytokeratin 7 Positive Immunoprofile are Different from Eosinophilic Chromophobe Renal Cell Carcinoma (ChrRCC) and Oncocytoma. United States and Canadian Academy of Pathology Annual Meeting 2018.