Difference between revisions of "Exaggerated placental site"

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#redirect [[Gestational_trophoblastic_disease#Exaggerated_placental_site]]
'''Exaggerated placental site''', abbreviated '''EPS''', is an uncommon benign pathology that is a
[[gestational trophoblastic disease]].


It was previously known as '''syncytial endometritis'''.<ref>URL: [http://www.webpathology.com/image.asp?case=565&n=7 http://www.webpathology.com/image.asp?case=565&n=7]. Accessed on: 22 May 2014.</ref>
==General==
*Benign.
Definition:
*"Increased number" of implantation-site [[Intermediate trophoblast|intermediate trophoblastic cells]].
Note:
*Used to go by a terrible old term: ''syncytial endometritis'':<ref name=ouhsc_kfung>URL: [http://moon.ouhsc.edu/kfung/IACP-OLP/TC-Text/TC-01-Supp.pdf http://moon.ouhsc.edu/kfung/IACP-OLP/TC-Text/TC-01-Supp.pdf]. Accessed on: 15 August 2011.</ref>
**Not syncytial -- mostly.
**Not inflammatory.
==Microscopic==
Features:<ref name=ouhsc_kfung/>
*Intermediate trophoblast:
**Abundant (eosinophilic) cytoplasm.
*Usu. adjacent to:
**[[Chorionic villi]].
**Decidua - endometrial stromal cells with a nucleus central, eosinphilic cytoplasm, well-defined cell borders.
*No mitotic activity.
*Ectatic blood vessels.
DDx:
*[[PSTT]].
==IHC==
*MIB1 ~0%.
**Used to differentiate from [[PSTT]].
==See also==
*[[Gestational trophoblastic disease]].
*[[Endometritis]].
==References==
{{Reflist|2}}
[[Category:Gestational trophoblastic disease]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 15:44, 22 May 2014

Exaggerated placental site, abbreviated EPS, is an uncommon benign pathology that is a gestational trophoblastic disease.

It was previously known as syncytial endometritis.[1]

General

  • Benign.

Definition:

Note:

  • Used to go by a terrible old term: syncytial endometritis:[2]
    • Not syncytial -- mostly.
    • Not inflammatory.

Microscopic

Features:[2]

  • Intermediate trophoblast:
    • Abundant (eosinophilic) cytoplasm.
  • Usu. adjacent to:
    • Chorionic villi.
    • Decidua - endometrial stromal cells with a nucleus central, eosinphilic cytoplasm, well-defined cell borders.
  • No mitotic activity.
  • Ectatic blood vessels.

DDx:

IHC

  • MIB1 ~0%.
    • Used to differentiate from PSTT.

See also

References