Difference between revisions of "Exaggerated placental site"
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'''Exaggerated placental site''', abbreviated '''EPS''', is an uncommon benign pathology that is a | |||
[[gestational trophoblastic disease]]. | |||
It was previously known as '''syncytial endometritis'''.<ref>URL: [http://www.webpathology.com/image.asp?case=565&n=7 http://www.webpathology.com/image.asp?case=565&n=7]. Accessed on: 22 May 2014.</ref> | |||
==General== | |||
*Benign. | |||
Definition: | |||
*"Increased number" of implantation-site [[Intermediate trophoblast|intermediate trophoblastic cells]]. | |||
Note: | |||
*Used to go by a terrible old term: ''syncytial endometritis'':<ref name=ouhsc_kfung>URL: [http://moon.ouhsc.edu/kfung/IACP-OLP/TC-Text/TC-01-Supp.pdf http://moon.ouhsc.edu/kfung/IACP-OLP/TC-Text/TC-01-Supp.pdf]. Accessed on: 15 August 2011.</ref> | |||
**Not syncytial -- mostly. | |||
**Not inflammatory. | |||
==Microscopic== | |||
Features:<ref name=ouhsc_kfung/> | |||
*Intermediate trophoblast: | |||
**Abundant (eosinophilic) cytoplasm. | |||
*Usu. adjacent to: | |||
**[[Chorionic villi]]. | |||
**Decidua - endometrial stromal cells with a nucleus central, eosinphilic cytoplasm, well-defined cell borders. | |||
*No mitotic activity. | |||
*Ectatic blood vessels. | |||
DDx: | |||
*[[PSTT]]. | |||
==IHC== | |||
*MIB1 ~0%. | |||
**Used to differentiate from [[PSTT]]. | |||
==See also== | |||
*[[Gestational trophoblastic disease]]. | |||
*[[Endometritis]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Gestational trophoblastic disease]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] |
Revision as of 15:44, 22 May 2014
Exaggerated placental site, abbreviated EPS, is an uncommon benign pathology that is a gestational trophoblastic disease.
It was previously known as syncytial endometritis.[1]
General
- Benign.
Definition:
- "Increased number" of implantation-site intermediate trophoblastic cells.
Note:
- Used to go by a terrible old term: syncytial endometritis:[2]
- Not syncytial -- mostly.
- Not inflammatory.
Microscopic
Features:[2]
- Intermediate trophoblast:
- Abundant (eosinophilic) cytoplasm.
- Usu. adjacent to:
- Chorionic villi.
- Decidua - endometrial stromal cells with a nucleus central, eosinphilic cytoplasm, well-defined cell borders.
- No mitotic activity.
- Ectatic blood vessels.
DDx:
- PSTT.
IHC
- MIB1 ~0%.
- Used to differentiate from PSTT.
See also
References
- ↑ URL: http://www.webpathology.com/image.asp?case=565&n=7. Accessed on: 22 May 2014.
- ↑ 2.0 2.1 URL: http://moon.ouhsc.edu/kfung/IACP-OLP/TC-Text/TC-01-Supp.pdf. Accessed on: 15 August 2011.