Difference between revisions of "Inflammatory pseudopolyp"
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'''Inflammatory pseudopolyp''' is a benign polypoid lesion usually seen in the context of [[inflammatory bowel disease]]. | |||
It is also referred to as '''inflammatory polyp'''. | |||
==General== | |||
*Not a true polyp. | |||
*The label ''inflammatory pseudopolyp'' = [[inflammatory bowel disease]] (IBD). | |||
**If there is no history of IBD... reconsider the diagnosis. | |||
==Microscopic== | |||
Features: | |||
*Polypoid shape. | |||
*Inflammation - esp. neutrophils - '''key feature'''. | |||
Negatives: | |||
*No nuclear atypia. | |||
**May have focal nuclear hyperchromasia and nuclear enlargement. | |||
*No dilated glands. | |||
DDx: | |||
*[[Juvenile polyp]]. | |||
*[[Mucosal prolapse]].<ref name=pmid21607734>{{Cite journal | last1 = Aust | first1 = DE. | last2 = Rüschoff | first2 = J. | title = [Polyps of the colorectum: non-neoplastic and non-hamartomatous]. | journal = Pathologe | volume = 32 | issue = 4 | pages = 297-302 | month = Jul | year = 2011 | doi = 10.1007/s00292-011-1435-1 | PMID = 21607734 }}</ref> | |||
**[[Solitary rectal ulcer]]. | |||
Images: | |||
*[http://www.humpath.com/spip.php?article8234&id_document=18554 Pseudopolyp (humpath.com)]. | |||
*[http://missinglink.ucsf.edu/lm/IDS_106_LowerGI/Lower_GI_histo_small/24-UC-pseudoplp.jpg Pseudopolyp (ucsf.edu)]. | |||
==Sign out== | |||
<pre> | |||
SIGMOID COLON POLYP, PERI-DIVERTICULAR, BIOPSY: | |||
- INFLAMMATORY PSEUDOPOLYP. | |||
</pre> | |||
<pre> | |||
POLYP, DESCENDING COLON, BIOPSY: | |||
- INFLAMED POLYPOID FRAGMENT OF COLORECTAL-TYPE MUCOSA. | |||
-- NEGATIVE FOR DYSPLASIA. | |||
</pre> | |||
===Micro=== | |||
The sections show a fragment of colorectal mucosa with focal ulceration, acute inflammation and a well-vascularized stroma with plump stromal cells. Occasional stromal cells have nuclear hyperchromasia. | |||
==See also== | |||
*[[Gastrointestinal tract polyps]]. | |||
*[[Mucosal prolapse syndrome]]. | |||
*[[Colon]]. | |||
*[[Nasal polyps]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Revision as of 10:17, 24 July 2013
Inflammatory pseudopolyp is a benign polypoid lesion usually seen in the context of inflammatory bowel disease.
It is also referred to as inflammatory polyp.
General
- Not a true polyp.
- The label inflammatory pseudopolyp = inflammatory bowel disease (IBD).
- If there is no history of IBD... reconsider the diagnosis.
Microscopic
Features:
- Polypoid shape.
- Inflammation - esp. neutrophils - key feature.
Negatives:
- No nuclear atypia.
- May have focal nuclear hyperchromasia and nuclear enlargement.
- No dilated glands.
DDx:
Images:
Sign out
SIGMOID COLON POLYP, PERI-DIVERTICULAR, BIOPSY: - INFLAMMATORY PSEUDOPOLYP.
POLYP, DESCENDING COLON, BIOPSY: - INFLAMED POLYPOID FRAGMENT OF COLORECTAL-TYPE MUCOSA. -- NEGATIVE FOR DYSPLASIA.
Micro
The sections show a fragment of colorectal mucosa with focal ulceration, acute inflammation and a well-vascularized stroma with plump stromal cells. Occasional stromal cells have nuclear hyperchromasia.
See also
References
- ↑ Aust, DE.; Rüschoff, J. (Jul 2011). "[Polyps of the colorectum: non-neoplastic and non-hamartomatous].". Pathologe 32 (4): 297-302. doi:10.1007/s00292-011-1435-1. PMID 21607734.