Difference between revisions of "Thrombotic thrombocytopenic purpura"
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''HUS/TTP is a CRAFTY syndrome'':<ref>URL: [http://www.valuemd.com/mnemonics2.php http://www.valuemd.com/mnemonics2.php]. Accessed on: 8 November 2010.</ref> | ''[[HUS]]/TTP is a CRAFTY syndrome'':<ref>URL: [http://www.valuemd.com/mnemonics2.php http://www.valuemd.com/mnemonics2.php]. Accessed on: 8 November 2010.</ref> | ||
*'''C'''NS symptoms. | *'''C'''NS symptoms. | ||
*'''R'''enal failure. | *'''R'''enal failure. | ||
Revision as of 12:50, 27 February 2012
Thrombotic thrombocytopenic purpura, abbreviated TTP, is a type of thrombotic microangiopathy.
Classic pentad
It was classically described as the pentad of:[1]
- Fever.
- Thrombocytopenia.
- Microangiopathic hemolytic anemia.
- Transient neurologic symptoms.
- Renal failure.
Mnemonic
HUS/TTP is a CRAFTY syndrome:[3]
- CNS symptoms.
- Renal failure.
- Anemia - microangiopathic hemolytic anemia.
- Fever.
- Thrombocytopenia.
- Y - no one knows "Y" it occurs.
Etiology
Deficiency of plasma enzyme ADAMTS13 which may be:[1]
- Inherited.
- Acquired (autoantibodies).
See also
References
- ↑ 1.0 1.1 Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 669. ISBN 978-1416031215.
- ↑ Klatt, Edward C. (2006). Robbins and Cotran Atlas of Pathology (1st ed.). Saunders. pp. 65. ISBN 978-1416002741.
- ↑ URL: http://www.valuemd.com/mnemonics2.php. Accessed on: 8 November 2010.