Difference between revisions of "Zollinger-Ellison syndrome"
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*Abdominal pain. | *Abdominal pain. | ||
*Diarrhea. | *Diarrhea. | ||
Laboratory: | |||
*Serum gastrin often elevated - though not usually not very high.<ref name=pmid17108778>{{Cite journal | last1 = Berna | first1 = MJ. | last2 = Hoffmann | first2 = KM. | last3 = Serrano | first3 = J. | last4 = Gibril | first4 = F. | last5 = Jensen | first5 = RT. | title = Serum gastrin in Zollinger-Ellison syndrome: I. Prospective study of fasting serum gastrin in 309 patients from the National Institutes of Health and comparison with 2229 cases from the literature. | journal = Medicine (Baltimore) | volume = 85 | issue = 6 | pages = 295-330 | month = Nov | year = 2006 | doi = 10.1097/01.md.0000236956.74128.76 | PMID = 17108778 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 22:26, 29 April 2013
Zollinger-Ellison syndrome, abbreviated ZES, is the triad of pancreatic gastrinoma, peptic ulcers of the small bowel and gastric hypersecretion.[1]
General
- May be part of multiple endocrine neoplasia 1.
Clinical:
- Abdominal pain.
- Diarrhea.
Laboratory:
- Serum gastrin often elevated - though not usually not very high.[2]
Microscopic
See also
References
- ↑ Zollinger RM, Ellison EH (1955). "Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas". Ann. Surg. 142 (4): 709–23; discussion, 724–8. doi:10.1097/00000658-195510000-00015. PMC 1465210. PMID 13259432. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1465210/.
- ↑ Berna, MJ.; Hoffmann, KM.; Serrano, J.; Gibril, F.; Jensen, RT. (Nov 2006). "Serum gastrin in Zollinger-Ellison syndrome: I. Prospective study of fasting serum gastrin in 309 patients from the National Institutes of Health and comparison with 2229 cases from the literature.". Medicine (Baltimore) 85 (6): 295-330. doi:10.1097/01.md.0000236956.74128.76. PMID 17108778.