Difference between revisions of "Mesonephric remnant of the prostate gland"

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==General==
==General==
*Very rare.<ref name=pmid21606823>{{Cite journal  | last1 = Chen | first1 = YB. | last2 = Fine | first2 = SW. | last3 = Epstein | first3 = JI. | title = Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy. | journal = Am J Surg Pathol | volume = 35 | issue = 7 | pages = 1054-61 | month = Jul | year = 2011 | doi = 10.1097/PAS.0b013e318218df97 | PMID = 21606823 }}</ref>
*Very rare.<ref name=pmid21606823>{{Cite journal  | last1 = Chen | first1 = YB. | last2 = Fine | first2 = SW. | last3 = Epstein | first3 = JI. | title = Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy. | journal = Am J Surg Pathol | volume = 35 | issue = 7 | pages = 1054-61 | month = Jul | year = 2011 | doi = 10.1097/PAS.0b013e318218df97 | PMID = 21606823 }}</ref> ~ 0.6% incidence in a series of almost 700 [[TURP]] specimens.<ref name=pmid12861057>{{Cite journal  | last1 = Bostwick | first1 = DG. | last2 = Qian | first2 = J. | last3 = Ma | first3 = J. | last4 = Muir | first4 = TE. | title = Mesonephric remnants of the prostate: incidence and histologic spectrum. | journal = Mod Pathol | volume = 16 | issue = 7 | pages = 630-5 | month = Jul | year = 2003 | doi = 10.1097/01.MP.0000074733.10777.78 | PMID = 12861057 }}</ref>
*Can mimic prostate carcinoma.
*Can mimic prostate carcinoma.<ref name=pmid19917478>{{Cite journal  | last1 = Yacoub | first1 = M. | last2 = Milin | first2 = S. | last3 = Irani | first3 = J. | last4 = Fromont | first4 = G. | title = Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer. | journal = Ann Diagn Pathol | volume = 13 | issue = 6 | pages = 402-4 | month = Dec | year = 2009 | doi = 10.1016/j.anndiagpath.2009.03.008 | PMID = 19917478 }}</ref>


==Microscopic==
==Microscopic==
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*[[Sclerosing adenosis]] of the prostate gland.
*[[Sclerosing adenosis]] of the prostate gland.
*[[Prostate carcinoma]] - esp. Gleason pattern 5.
*[[Prostate carcinoma]] - esp. Gleason pattern 5.
===Images===
www:
*[http://www.nature.com/modpathol/journal/v16/n7/fig_tab/3880816f1.html#figure-title Mesonephric remnants (nature.com)].<ref name=pmid12861057/>


==IHC==
==IHC==
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*PAX8 +ve.
*PAX8 +ve.
*PSA -ve (all).
*PSA -ve (all).
*PSAP -ve.<ref name=pmid12861057>{{Cite journal  | last1 = Bostwick | first1 = DG. | last2 = Qian | first2 = J. | last3 = Ma | first3 = J. | last4 = Muir | first4 = TE. | title = Mesonephric remnants of the prostate: incidence and histologic spectrum. | journal = Mod Pathol | volume = 16 | issue = 7 | pages = 630-5 | month = Jul | year = 2003 | doi = 10.1097/01.MP.0000074733.10777.78 | PMID = 12861057 }</ref>
*CK34betaE12 +ve/-ve (diffuse +ve in 4/7 cases)
*CK34betaE12 +ve/-ve (diffuse +ve in 4/7 cases)
*p63 -ve.
*p63 -ve.
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==References==
==References==
{{Reflist|1}}
{{Reflist|2}}


[[Category:Prostate gland]]
[[Category:Prostate gland]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 14:40, 9 April 2014

Mesonephric remnant hyperplasia of the prostate gland, also mesonephric remnant, is rare benign finding in the prostate gland that can be confused with malignancy.

General

  • Very rare.[1] ~ 0.6% incidence in a series of almost 700 TURP specimens.[2]
  • Can mimic prostate carcinoma.[3]

Microscopic

Features:[1]

  • Small glands with small bland appearing cuboidal cells in a lobular arrangement.

DDx:[1]

Images

www:

IHC

Features:[1]

  • PAX8 +ve.
  • PSA -ve (all).
  • PSAP -ve.[2]
  • CK34betaE12 +ve/-ve (diffuse +ve in 4/7 cases)
  • p63 -ve.
  • AMACR +ve (focal).

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 Chen, YB.; Fine, SW.; Epstein, JI. (Jul 2011). "Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy.". Am J Surg Pathol 35 (7): 1054-61. doi:10.1097/PAS.0b013e318218df97. PMID 21606823.
  2. ↑ 2.0 2.1 2.2 Bostwick, DG.; Qian, J.; Ma, J.; Muir, TE. (Jul 2003). "Mesonephric remnants of the prostate: incidence and histologic spectrum.". Mod Pathol 16 (7): 630-5. doi:10.1097/01.MP.0000074733.10777.78. PMID 12861057. Cite error: Invalid <ref> tag; name "pmid12861057" defined multiple times with different content
  3. ↑ Yacoub, M.; Milin, S.; Irani, J.; Fromont, G. (Dec 2009). "Mesonephric remnant hyperplasia: an unusual benign mimicker of prostate cancer.". Ann Diagn Pathol 13 (6): 402-4. doi:10.1016/j.anndiagpath.2009.03.008. PMID 19917478.
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