Difference between revisions of "Follicular thyroid adenoma"
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'''Follicular thyroid adenoma''', abbreviated ''FTA'', is a benign lesion of the [[thyroid gland]]. | '''Follicular thyroid adenoma''', abbreviated '''FTA''', is a benign lesion of the [[thyroid gland]]. | ||
==General== | ==General== | ||
Revision as of 03:27, 4 March 2015
Follicular thyroid adenoma, abbreviated FTA, is a benign lesion of the thyroid gland.
General
- Most common neoplasm of thyroid.[1]
- Encapusled lesion (surrounded by fibrous capsule).
Gross
- Thick capsule.
Notes:
- The entire capsule should be submitted.[2]
- A good start for most thyroid specimens with a thick capsule is 10 blocks.
Microsopic
Features:
- Cellular.
- Thick capsule - key feature.
Negatives.
- No invasion of the capsule - see follicular thyroid carcinoma.
- No nuclear features suggestive of papillary thyroid carcinoma.
DDx:
- Thyroid gland nodular hyperplasia with an encapsulated nodule - not as cellular.
- Follicular thyroid carcinoma.
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LEFT THYROID, SUPERIOR POLE, EXCISION: - FOLLICULAR ADENOMA, MAXIMAL DIMENSION 5 MM. - LYMPHOCYTIC THYROIDITIS. - NODULAR HYPERPLASIA. - NEGATIVE FOR MALIGNANCY.
Micro
The section shows a well-circumscribed lesion encapsulated by a thick fibrous capsule (~0.4 mm thick).
The lesions consists of microfollicles with a dense appearing colloid. The nuclei have round regular nuclear membranes. Small indistinct nucleoli are seen at high power.
Focally, the lesional cells overlap. However, the chromatin is not cleared. Nuclear grooves are not readily apparent and nuclear pseudoinclusions are not readily identified.
See also
References
- ↑ Thompson, Lester D. R. (2006). Endocrine Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 51. ISBN 978-0443066856.
- ↑ SR. 17 January 2011.