Difference between revisions of "GATA3"
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===Images=== | ===Images=== | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444740/figure/F1/ GATA3 nuclear staining - urothelial carcinoma (nih.gov)].<ref name=pmid22982890 | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444740/figure/F1/ GATA3 nuclear staining - urothelial carcinoma (nih.gov)].<ref name=pmid22982890/> | ||
==Negative== | ==Negative== | ||
*[[Prostate carcinoma]]. | *[[Prostate carcinoma]]. | ||
*[[Squamous cell carcinoma of the lung]].<ref name=pmid22982890 | *[[Squamous cell carcinoma of the lung]].<ref name=pmid22982890/> | ||
==See also== | ==See also== | ||
Revision as of 14:17, 14 April 2016
| GATA3 | |
|---|---|
| Immunostain in short | |
 GATA3 staining in benign urothelium. | |
| Use | bladder versus prostate, bladder versus SCC |
| Subspeciality | Genitourinary pathology |
| Normal staining pattern | nuclear |
| Positive | urothelial carcinoma, lobular breast carcinoma |
| Negative | prostatic carcinoma, squamous cell carcinoma of the lung |
GATA3 an immunostain that is increasingly used in genitourinary pathology.
Positive
Images
Negative
See also
References
- ↑ 1.0 1.1 1.2 Chang A, Amin A, Gabrielson E, et al. (October 2012). "Utility of GATA3 immunohistochemistry in differentiating urothelial carcinoma from prostate adenocarcinoma and squamous cell carcinomas of the uterine cervix, anus, and lung". Am. J. Surg. Pathol. 36 (10): 1472–6. doi:10.1097/PAS.0b013e318260cde7. PMC 3444740. PMID 22982890. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444740/.
- ↑ Ellis, CL.; Chang, AG.; Cimino-Mathews, A.; Argani, P.; Youssef, RF.; Kapur, P.; Montgomery, EA.; Epstein, JI. (Nov 2013). "GATA-3 immunohistochemistry in the differential diagnosis of adenocarcinoma of the urinary bladder.". Am J Surg Pathol 37 (11): 1756-60. doi:10.1097/PAS.0b013e31829cdba7. PMID 24061521.