Difference between revisions of "Eye"
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Features: | Features: | ||
*[[Small round cell tumour]]. | *[[Small round cell tumour]]. | ||
*Flexner-Wintersteiner [[rosette]]. | *Flexner-Wintersteiner [[rosette]] - '''key feature'''. | ||
**Rosette with empty centre (donut hole).<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref> | **Rosette with empty centre (donut hole).<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref> | ||
*+/-Homer-Wright rosette.<ref>WH. 14 March 2011.</ref> | |||
**Circular rosette with neuropil at the centre.<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref> | |||
Image: | Image: | ||
Revision as of 15:08, 14 March 2011
The eye is rarely seen by pathologists. They go to neuropathologists.
An introduction to neuropathology is in the neuropathology article.
Histology
- The muscles that move the eye have a high nerve:muscle ratio = ~1:4.[1]
- Other muscles in the body ~1:250.
Retinoblastoma
General
- Rare.
- Malignant.
- May be familial.[2]
Microscopic
Features:
- Small round cell tumour.
- Flexner-Wintersteiner rosette - key feature.
- Rosette with empty centre (donut hole).[3]
- +/-Homer-Wright rosette.[4]
- Circular rosette with neuropil at the centre.[3]
Image:
Notes:
- DDx of Flexner-Wintersteiner rosette includes: pineoblastomas, medulloepitheliomas.
Retinal hemorrhage
Image:
See also
References
- ↑ Bilbao. 24 November 2010.
- ↑ Lohmann D (2010). "Retinoblastoma". Adv. Exp. Med. Biol. 685: 220–7. PMID 20687510.
- ↑ 3.0 3.1 Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.
- ↑ WH. 14 March 2011.
- ↑ URL: http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/fofrm.html. Accessed on: 6 December 2010.