Difference between revisions of "Pleural plaque"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = hyaline (fibrosis) material +/-[[calcification]]s | |||
| Subtypes = | |||
| LMDDx = [[fibrosing pleuritis]], [[malignant mesothelioma]] - especially [[desmoplastic mesothelioma]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = white pleural lesions | |||
| Grossing = | |||
| Staging = | |||
| Site = [[pleural]] | |||
| Assdx = [[asbestosis]], [[malignant mesothelioma]] | |||
| Syndromes = | |||
| Clinicalhx = exposure to asbestos | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = pleural thickening | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = [[malignant mesothelioma]], metastatic [[carcinoma]] | |||
| Tx = | |||
}} | |||
A '''pleural plaque''' is a benign fibrous thickening of the [[pleura]]. It is strongly associated with asbestos exposure.<ref name=pmid22617814>{{Cite journal | last1 = Myers | first1 = R. | title = Asbestos-related pleural disease. | journal = Curr Opin Pulm Med | volume = 18 | issue = 4 | pages = 377-81 | month = Jul | year = 2012 | doi = 10.1097/MCP.0b013e328354acfe | PMID = 22617814 }}</ref> | A '''pleural plaque''' is a benign fibrous thickening of the [[pleura]]. It is strongly associated with asbestos exposure.<ref name=pmid22617814>{{Cite journal | last1 = Myers | first1 = R. | title = Asbestos-related pleural disease. | journal = Curr Opin Pulm Med | volume = 18 | issue = 4 | pages = 377-81 | month = Jul | year = 2012 | doi = 10.1097/MCP.0b013e328354acfe | PMID = 22617814 }}</ref> | ||
Revision as of 01:07, 14 June 2016
| Pleural plaque | |
|---|---|
| Diagnosis in short | |
|
| |
| LM | hyaline (fibrosis) material +/-calcifications |
| LM DDx | fibrosing pleuritis, malignant mesothelioma - especially desmoplastic mesothelioma |
| Gross | white pleural lesions |
| Site | pleural |
|
| |
| Associated Dx | asbestosis, malignant mesothelioma |
| Clinical history | exposure to asbestos |
| Prevalence | uncommon |
| Radiology | pleural thickening |
| Prognosis | benign |
| Clin. DDx | malignant mesothelioma, metastatic carcinoma |
A pleural plaque is a benign fibrous thickening of the pleura. It is strongly associated with asbestos exposure.[1]
General
- May be due to other causes.[2]
Other asbestos-related pleural disease:[1]
- Diffuse pleural thickening.
- Benign asbestos-related pleural effusions (BAPEs).
- Malignant mesothelioma.
Gross
- Thickened (or calcified) plaques.[2]
- White.
DDx:
- Metastatic carcinoma.
Images
Fibrous pleural plaque. (WC/Rosen)
.jpg)
Microscopic
Features:[3]
- Hyaline material +/- calcification.
Notes:
- Usually associated with asbestosis fibres in the lung (85% of cases).[3]
- Plaque burden seems to be associated with the number asbestos bodies found; many plaques... suggest many asbestosis bodies.
DDx:
Images
See also
- Asbestosis - lung has fibrosis.
- Malignant mesothelioma.
- Ferruginous bodies.
References
- ↑ 1.0 1.1 Myers, R. (Jul 2012). "Asbestos-related pleural disease.". Curr Opin Pulm Med 18 (4): 377-81. doi:10.1097/MCP.0b013e328354acfe. PMID 22617814.
- ↑ 2.0 2.1 Clarke, CC.; Mowat, FS.; Kelsh, MA.; Roberts, MA.. "Pleural plaques: a review of diagnostic issues and possible nonasbestos factors.". Arch Environ Occup Health 61 (4): 183-92. doi:10.3200/AEOH.61.4.183-192. PMID 17867573.
- ↑ 3.0 3.1 Roberts, GH. (May 1971). "The pathology of parietal pleural plaques.". J Clin Pathol 24 (4): 348-53. PMID 5556121.