Difference between revisions of "Low-grade oncocytic renal tumour"
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'''Renal oncocytic tumour that is CD117 negative and CK7 positive''' is unusual [[renal tumour]] that does not neatly fit into any WHO renal neoplasia category. | '''Renal oncocytic tumour that is CD117 negative and CK7 positive''', also known as '''low grade oncocytic renal tumour''', is unusual [[renal tumour]] that does not neatly fit into any WHO renal neoplasia category. | ||
==General== | ==General== | ||
| Line 17: | Line 17: | ||
*[[Renal cell carcinoma, unclassified]]. | *[[Renal cell carcinoma, unclassified]]. | ||
*[[Renal tumours with eosinophilic cytoplasm]]. | *[[Renal tumours with eosinophilic cytoplasm]]. | ||
===Images=== | |||
<gallery> | |||
Image: Low grade oncocytic renal tumour -- low mag.jpg | LGORT - low mag. (WC) | |||
Image: Low grade oncocytic renal tumour -- intermed mag.jpg | LGORT - intermed. mag. (WC) | |||
Image: Low grade oncocytic renal tumour - alt -- intermed mag.jpg | LGORT - intermed. mag. (WC) | |||
Image: Low grade oncocytic renal tumour -- high mag.jpg | LGORT - high mag. (WC) | |||
Image: Low grade oncocytic renal tumour - alt - high mag.jpg | LGORT - high mag. (WC) | |||
Image: Low grade oncocytic renal tumour - very high mag.jpg | LGORT - high mag. (WC) | |||
</gallery> | |||
==IHC== | ==IHC== | ||
Revision as of 04:36, 3 March 2019
Renal oncocytic tumour that is CD117 negative and CK7 positive, also known as low grade oncocytic renal tumour, is unusual renal tumour that does not neatly fit into any WHO renal neoplasia category.
General
- Very rare.
Microscopic
Features:[1]
- Oncocytic cytoplasm.
- Round nuclei.
- Tubular or solid architecture.
- Edematous areas with loosly arranged cells.
DDx:
- Renal oncocytoma.
- Chromophobe renal cell carcinoma.
- Renal hybrid oncocytic/chromophobe tumour.
- Renal cell carcinoma, unclassified.
- Renal tumours with eosinophilic cytoplasm.
Images
LGORT - low mag. (WC)
LGORT - intermed. mag. (WC)
LGORT - intermed. mag. (WC)
LGORT - high mag. (WC)
LGORT - high mag. (WC)
- Low grade oncocytic renal tumour - very high mag.jpg
LGORT - high mag. (WC)
IHC
Features:
- CD10 -ve/+ve.
- AMACR -ve/+ve.
- CA9 -ve.
- CK20 -ve.
See also
References
- ↑ Trpkov K, Williamson S, Martinek P, Cheng L, San Miguel Fraile P, Yilmaz A, Hes O, Oncocytic Renal Tumors with CD117 Negative, Cytokeratin 7 Positive Immunoprofile are Different from Eosinophilic Chromophobe Renal Cell Carcinoma (ChrRCC) and Oncocytoma. United States and Canadian Academy of Pathology Annual Meeting 2018.