Difference between revisions of "Tuberous sclerosis"

From Libre Pathology
Jump to navigation Jump to search
(more)
Line 14: Line 14:


Note:
Note:
*The same genes (TSC1<ref>{{OMIM|605284}}</ref>, TSC2<ref>{{OMIM|191092}}</ref>) are implicated in [[PEComa]]s.
*The same genes (TSC1, TSC2) are implicated in [[PEComa]]s.
 
==Genes==
*TSC1.<ref>{{OMIM|605284}}</ref>
*TSC2.<ref>{{OMIM|191092}}</ref>


==Incidence==
==Incidence==

Revision as of 04:59, 29 July 2011

Tuberous sclerosis, also tuberous sclerosis complex - abbreviated TSC, is genetic thingy associated with increased risk of hamartomas.

Historically described as:[1]

  1. Epilepsy.
  2. Mental retardation.
  3. Adenoma sebaceum.

Associations

Pathologic:

Note:

  • The same genes (TSC1, TSC2) are implicated in PEComas.

Genes

Incidence

~1 in 10,000 population.[1]

See also

References

  1. ↑ 1.0 1.1 URL: http://emedicine.medscape.com/article/1177711-overview. Accessed on: 13 February 2011.
  2. ↑ Grajkowska, W.; Kotulska, K.; Jurkiewicz, E.; Roszkowski, M.; Daszkiewicz, P.; Jóźwiak, S.; Matyja, E. (2011). "Subependymal giant cell astrocytomas with atypical histological features mimicking malignant gliomas.". Folia Neuropathol 49 (1): 39-46. PMID 21455842.
  3. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 605284
  4. ↑ Online 'Mendelian Inheritance in Man' (OMIM) 191092
Retrieved from "https://librepathology.org/w/index.php?title=Tuberous_sclerosis&oldid=6121"