Difference between revisions of "Mast cell"

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==Diseases==
==Diseases==
*[[Mastocytosis]].
*[[Mastocytosis]].
**Urticaria pigmentosa.
*[[Asthma]].<ref name=Ref_PCPBoD8_370-2>{{Ref PCPBoD8|370-2}}</ref>
*[[Asthma]].<ref name=Ref_PCPBoD8_370-2>{{Ref PCPBoD8|370-2}}</ref>



Revision as of 18:13, 8 September 2011

The mast cell is an uncommonly cell that occasionally causes problems.

Microscopic

Features:

  • Ovoid/round cell with moderate amount of gray granular cytoplasm.
  • Nuclear ovoid/round.
    • No obvious nucleolus.
  • May be more abundant around blood vessels.

Notes:

  • Lymphocyte vs. mast cell:
    • Lymphocytes = round; mast cells = ovoid.

Image:

Diseases

Stains

IHC

  • CD117 +ve.

References

  1. URL: http://www.jameswpattersonmd.com/case_studies/index.cfm?CFID=387434. Accessed on: 7 September 2011.
  2. Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 370-2. ISBN 978-1416054542.