Difference between revisions of "Bacteria"

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==Actinobacteria==
==Actinobacteria==
*Previously known ''actinomycetes''.
===General===
*A very large group of bacteria.
 
It includes:<ref name=pmid17804669>{{Cite journal  | last1 = Ventura | first1 = M. | last2 = Canchaya | first2 = C. | last3 = Tauch | first3 = A. | last4 = Chandra | first4 = G. | last5 = Fitzgerald | first5 = GF. | last6 = Chater | first6 = KF. | last7 = van Sinderen | first7 = D. | title = Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum. | journal = Microbiol Mol Biol Rev | volume = 71 | issue = 3 | pages = 495-548 | month = Sep | year = 2007 | doi = 10.1128/MMBR.00005-07 | PMID = 17804669 | PMC = 2168647}}</ref>
*Actinomycetes.
*Corynebacterium.
*Mycobacterium.
*Nocardia.
*Streptomyces.


==Actinomycetes==
===General===
===General===
*IUD needs to be removed if found on a pap test<ref name=Ref_WMSP446>{{Ref WMSP|446}}</ref> - see ''[[Gynecologic cytopathology#Actinomycetes|gynecologic cytopathology]]''.
*IUD needs to be removed if found on a pap test<ref name=Ref_WMSP446>{{Ref WMSP|446}}</ref> - see ''[[Gynecologic cytopathology#Actinomycetes|gynecologic cytopathology]]''.
*Gram-positive branching rods.
*Gram-positive branching rods.
*Common in the tonsils.
*Common in the tonsils.
*Part of the large [[Actinobacteria]] group.<ref name=pmid17804669>{{Cite journal  | last1 = Ventura | first1 = M. | last2 = Canchaya | first2 = C. | last3 = Tauch | first3 = A. | last4 = Chandra | first4 = G. | last5 = Fitzgerald | first5 = GF. | last6 = Chater | first6 = KF. | last7 = van Sinderen | first7 = D. | title = Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum. | journal = Microbiol Mol Biol Rev | volume = 71 | issue = 3 | pages = 495-548 | month = Sep | year = 2007 | doi = 10.1128/MMBR.00005-07 | PMID = 17804669 | PMC = 2168647}}</ref>


Notes:
Notes:

Revision as of 16:41, 15 September 2011

Bacteria are single celled microorganisms, without a nucleus (prokaryotes), that can cause lots of morbidity and mortality. They are not infrequently seen by pathologists.

Actinobacteria

General

  • A very large group of bacteria.

It includes:[1]

  • Actinomycetes.
  • Corynebacterium.
  • Mycobacterium.
  • Nocardia.
  • Streptomyces.

Actinomycetes

General

Notes:

  • Mycete = fungus; these organisms have a fungus-like appearance.

Gross

  • Yellow granules.[3]

Microscopic

Features:[4][3]

  • Branching rods.
  • Typically form pink/purple granules ("sulfur granule") that is surrounded by inflammatory cells (lymphocytes or neutrophils).

DDx:

  • Nocardia.

Notes:

  • Sulfur granule may be seen grossly - yellow.[3]

Images:

Stains

  • Gram +ve.
  • AFB -ve.
    • Nocardia +ve.

Helicobacter pylori

See Stomach.

Clostridium difficile

  • Commonly C. difficile.

General

  • Gram positive bacillus.

One virulent strain is:[5][6] BI/NAP1.

  • Deletion of tcdC locus.
  • Resistant to fluoroquinolones (gatifloxacin and moxifloxacin).

See also

References

  1. 1.0 1.1 Ventura, M.; Canchaya, C.; Tauch, A.; Chandra, G.; Fitzgerald, GF.; Chater, KF.; van Sinderen, D. (Sep 2007). "Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum.". Microbiol Mol Biol Rev 71 (3): 495-548. doi:10.1128/MMBR.00005-07. PMC 2168647. PMID 17804669. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168647/.
  2. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 446. ISBN 978-0781765275.
  3. 3.0 3.1 3.2 URL: http://pathmicro.med.sc.edu/mycology/mycology-2.htm. Accessed on: 14 September 2011.
  4. URL: http://pathology.class.kmu.edu.tw/ch05/Slide42.htm . Accessed on: 14 September 2011.
  5. URL: http://www.medpagetoday.com/InfectiousDisease/PublicHealth/2254. Accessed on: 15 August 2011.
  6. McDonald, LC.; Killgore, GE.; Thompson, A.; Owens, RC.; Kazakova, SV.; Sambol, SP.; Johnson, S.; Gerding, DN. (Dec 2005). "An epidemic, toxin gene-variant strain of Clostridium difficile.". N Engl J Med 353 (23): 2433-41. doi:10.1056/NEJMoa051590. PMID 16322603.