Difference between revisions of "Thrombotic thrombocytopenic purpura"
Jump to navigation
Jump to search
(+cat.) |
(+abbrev.) |
||
| Line 1: | Line 1: | ||
'''Thrombotic thrombocytopenic purpura''' is a type of [[thrombotic microangiopathy]]. | '''Thrombotic thrombocytopenic purpura''', abbreviated '''TTP''', is a type of [[thrombotic microangiopathy]]. | ||
==Classic pentad== | ==Classic pentad== | ||
Revision as of 04:29, 29 October 2011
Thrombotic thrombocytopenic purpura, abbreviated TTP, is a type of thrombotic microangiopathy.
Classic pentad
It was classically described as the pentad of:[1]
- Fever.
- Thrombocytopenia.
- Microangiopathic hemolytic anemia.
- Transient neurologic symptoms.
- Renal failure.
Mnemonic
HUS/TTP is a CRAFTY syndrome:[3]
- CNS symptoms.
- Renal failure.
- Anemia - microangiopathic hemolytic anemia.
- Fever.
- Thrombocytopenia.
- Y - no one knows "Y" it occurs.
Etiology
Deficiency of plasma enzyme ADAMTS13 which may be:[1]
- Inherited.
- Acquired (autoantibodies).
See also
References
- ↑ 1.0 1.1 Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 669. ISBN 978-1416031215.
- ↑ Klatt, Edward C. (2006). Robbins and Cotran Atlas of Pathology (1st ed.). Saunders. pp. 65. ISBN 978-1416002741.
- ↑ URL: http://www.valuemd.com/mnemonics2.php. Accessed on: 8 November 2010.