Haematopoiesis
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Haematopoiesis is the making of blood. Problems in haematopoiesis are numberous and the domain of hematology and hematopathology.
Normal haematopoiesis
Microscopic
One should see three cell lines:[1]
- Erythroid (red blood cells).
- Myeloid (white blood cells).
- Megakaryocytic (platelets).
Images:
- Extramedullary haematopoiesis - sort-of - high mag. (WC) - shows nucleated RBCs.
- Megakaryocyte (ouhsc.edu).[2]
Extramedullary haematopoiesis
- Abbreviated EMH.
General
- In adults it is a compensatory mechanism for bone marrow dysfunction.
Locations:[3]
Microscopic
Features:
- Erythroid cells - esp. nucleated red blood cells.
- Myeloid - granulocytes and granulocyte precursors.
- Megakaryocytes - Large cells (50-100 μm) with abundant cytoplasm.
- Make platelets.
Images:
See also
References
- ↑ URL: http://emedicine.medscape.com/article/199003-overview. Accessed on: 22 November 2010.
- ↑ URL: http://www.ouhsc.edu/histology/Text%20Sections/Hematopoiesis.html. Accessed on: 22 November 2010.
- ↑ URL: http://path.upmc.edu/cases/case283/dx.html. Accessed on: 14 January 2012.