Malakoplakia

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Malakoplakia is a thingy that typically arises in the bladder.

Gross

  • Yellow mass.[1]
    • May mimic renal cell carcinoma.

Microscopic

Features:[2]

  • Basophilic calcified lysosomes (Michaelis-Gutmann bodies) -- key feature.
    • May be inside or outside of macrophages - often size of RBC or larger.
  • Large foamy macrophages with granular cytoplasm.
  • Occasional multinucleated giant cell.
  • Lymphocytes.

Images:

See also

References

  1. ↑ URL: http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)70719-7. Accessed on: 9 September 2010.
  2. ↑ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. pp. 1027. ISBN 0-7216-0187-1.
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