Female adnexal tumour of probable Wolffian origin

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Female adnexal tumour of probable Wolffian origin, abbreviated FATWO, is a rare usually benign tumour.

It is also known as Wolffian adnexal tumour.

General

  • Super rare.[1]
  • Adnexal - as the name suggests.
  • Usually benign.
    • May be malignant.[2]

Microscopic

Features:

  • Tubular/glandular spaces.

DDx:

Images

  • FATWO - intermed. mag.

  • FATWO - high mag.

  • FATWO - very high mag.

IHC

Features:[3]

  • Vimentin +ve.
  • AE1/AE3 +ve.
  • CAM5.2 +ve.
  • CK7 +ve -- focal, sometimes -ve.
  • AR +ve ~80% of cases.

Others:[3]

  • CK20 -ve.
  • mCEA -ve.

See also

References

  1. ↑ Tianmin, X.; Weiqim, C.; Mianhua, C.; Xiaocui, L.; Hongwen, G.; Min, Y. (2012). "Tumor of the mesosalpinx: case report of a female adnexal tumor of probable Wolffian origin.". Eur J Gynaecol Oncol 33 (2): 233-5. PMID 22611973.
  2. ↑ Heller, DS.; Kadire, B.; Cracchiolo, B.. "Malignant female adnexal tumor of probable Wolffian origin: a case report.". J Reprod Med 56 (3-4): 175-7. PMID 21542539.
  3. ↑ 3.0 3.1 Devouassoux-Shisheboran, M.; Silver, SA.; Tavassoli, FA. (Jul 1999). "Wolffian adnexal tumor, so-called female adnexal tumor of probable Wolffian origin (FATWO): immunohistochemical evidence in support of a Wolffian origin.". Hum Pathol 30 (7): 856-63. PMID 10414506.
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