Low-grade oncocytic renal tumour
Revision as of 18:24, 23 November 2018 by Michael (talk | contribs) (Michael moved page Renal oncocytic tumour that are CD117 negative and CK7 positive to Renal oncocytic tumour that is CD117 negative and CK7 positive: fix grammar)
Renal oncocytic tumour that are CD117 negative and CK7 positive is unusual renal tumour that does not neatly fit into any WHO renal neoplasia category.
General
- Very rare.
Microscopic
Features:[1]
- Oncocytic cytoplasm.
- Round nuclei.
- Tubular or solid architecture.
- Edematous areas with loosly arranged cells.
DDx:
- Renal oncocytoma.
- Chromophobe renal cell carcinoma.
- Renal hybrid oncocytic/chromophobe tumour.
- Renal cell carcinoma, unclassified.
IHC
Features:
- CD10 -ve/+ve.
- AMACR -ve/+ve.
- CA9 -ve.
- CK20 -ve.
See also
References
- ↑ Trpkov K, Williamson S, Martinek P, Cheng L, San Miguel Fraile P, Yilmaz A, Hes O, Oncocytic Renal Tumors with CD117 Negative, Cytokeratin 7 Positive Immunoprofile are Different from Eosinophilic Chromophobe Renal Cell Carcinoma (ChrRCC) and Oncocytoma. United States and Canadian Academy of Pathology Annual Meeting 2018.