Mast cell
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The mast cell is an uncommonly cell that occasionally causes problems.
Microscopic
Features:
- Ovoid/round cell with moderate amount of gray granular cytoplasm.
- Nuclear ovoid/round.
- No obvious nucleolus.
- May be more abundant around blood vessels.
Notes:
- Lymphocyte vs. mast cell:
- Lymphocytes = round; mast cells = ovoid.
Image:
Diseases
- Mastocytosis.
- Urticaria pigmentosa.
- Asthma.[2]
Stains
- Giemsa stain.
- Tyrosinase.[3]
IHC
- CD117 +ve.
References
- ↑ URL: http://www.jameswpattersonmd.com/case_studies/index.cfm?CFID=387434. Accessed on: 7 September 2011.
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 370-2. ISBN 978-1416054542.
- ↑ URL: http://www.nature.com/jid/journal/v53/n1/full/jid1969105a.html. Accessed on: 20 December 2011.