Mesonephric remnant of the prostate gland

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Mesonephric remnant hyperplasia of the prostate gland, also mesonephric remnant, is rare benign finding in the prostate gland that can be confused with malignancy.

General

  • Very rare.[1]
  • Can mimic prostate carcinoma.

Microscopic

Features:[1]

  • Small glands with small bland appearing cuboidal cells in a lobular arrangement.

DDx:[1]

IHC

Features:[1]

  • PAX8 +ve.
  • PSA -ve (all).
  • CK34betaE12 +ve/-ve (diffuse +ve in 4/7 cases)
  • p63 -ve.
  • AMACR +ve (focal).

See also

References

  1. 1.0 1.1 1.2 1.3 Chen, YB.; Fine, SW.; Epstein, JI. (Jul 2011). "Mesonephric remnant hyperplasia involving prostate and periprostatic tissue: findings at radical prostatectomy.". Am J Surg Pathol 35 (7): 1054-61. doi:10.1097/PAS.0b013e318218df97. PMID 21606823.