Thyroid transcription factor-1

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TTF-1 staining in lung adenocarcinoma.

Thyroid transcription factor-1, abbreviated TTF-1 is a transcription factor seen in lung and thyroid.^[1]

Positive staining

Nuclear staining.

Normal tissues

Thyroid gland.
Lung.

Tumours

Note:

TTF-1 is negative of squamous cell carcinoma of the lung.

See also

Immunohistochemistry.

References

↑ Ordóñez, NG. (Mar 2000). "Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas.". Adv Anat Pathol 7 (2): 123-7. PMID 10721419.
↑ Yatabe, Y.; Mitsudomi, T.; Takahashi, T. (Jun 2002). "TTF-1 expression in pulmonary adenocarcinomas.". Am J Surg Pathol 26 (6): 767-73. PMID 12023581.

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Immunohistochemistry