Lymphocytic gastritis

Lymphocytic gastritis
Diagnosis in short
Lymphocytic gastritis. H&E stain. (WC/Nephron)
LM	intraepithelial lymphocytes (>25 lymphocytes/100 epithelial cells)
Subtypes	primary (idiopathic), secondary
LM DDx	Helicobacter gastritis, Crohn's disease, lymphoma
Site	stomach
Associated Dx	celiac disease (common), HIV
Clinical history	dependent on underlying cause
Prevalence	rare
Prognosis	benign
Treatment	dependent underlying cause

Lymphocytic gastritis, abbreviated LG, is a rare form of gastritis, typically associated with celiac disease or Helicobacter pylori infection.

General

The DDx is limited:

1. Celiac disease - most common (39 of 82 cases in one series).
2. Helicobacter gastritis - common (30 of 82 cases in one series).
3. Idiopathic.
4. HIV/AIDS.
5. Crohn's disease.
6. Lymphoma.

Microscopic

Features:

• 25 lymphocytes / 100 epithelial cells.

DDx:

• Helicobacter gastritis - Helicobacter-like organisms present.
• Lymphoma - esp. MALT lymphoma.

Images

• 

  LG - low mag. (WC)

• 

  LG - intermed. mag. (WC)

• 

  LG - intermed. mag. (WC)

• 

  LG - high mag. (WC)

• 

  LG - high mag. (WC)

• 

  LG - high mag. (WC)

See also

• Gastritis.
• Lymphocytic colitis.
• Celiac disease.