Eccrine spiradenoma
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Eccrine spiradenoma, also spiradenoma,[1] is a benign skin thingy. There is case series of malignant ones.[2]
General
- A painful skin lesion.
- Benign.
Microscopic
Features:[3]
- Dense nests of cells in the dermis; "dermal blue balls".
- Apocrine differentiation, i.e. apocrine snouts.
Images:
- Eccrine spiradenoma - very low mag. (WC).
- Eccrine spiradenoma - very high mag. (WC).
- Eccrine spiradenoma (dermimages.med.jhmi.edu).[3]
IHC
Features:[4]
- S100 +ve.
- Keratins 7, 8, and 18 +ve.
Notes:
- IHC profile essentially identical to dermal cylindroma.[4]
See also
References
- ↑ URL: http://emedicine.medscape.com/article/1062079-overview. Accessed on: 9 May 2011.
- ↑ Andreoli, MT.; Itani, KM. (May 2011). "Malignant eccrine spiradenoma: a meta-analysis of reported cases.". Am J Surg 201 (5): 688-92. doi:10.1016/j.amjsurg.2010.04.015. PMID 20851376.
- ↑ 3.0 3.1 URL: http://www.dermatlas.com/derm/IndexDisplay.cfm?ImageID=-1193575448. Accessed on: 29 November 2010.
- ↑ 4.0 4.1 Meybehm, M.; Fischer, HP. (Apr 1997). "Spiradenoma and dermal cylindroma: comparative immunohistochemical analysis and histogenetic considerations.". Am J Dermatopathol 19 (2): 154-61. PMID 9129700.