Scleroderma

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Scleroderma is a disease that keeps rheumatologists busy.

General

Clinical:

Anti-centromere antibody +ve.
- Common in limited systemic scleroderma, AKA CREST Syndrome.
Scl-70 (topoisomerase I).
- Common in diffuse scleroderma.

Associated pathology

Scleroderma panniculitis.

See also

Basics.

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Clinical