Behçet's syndrome

Behçet's syndrome, also Behçet's disease, is a rare disorder classically described as the triad of:

1. Oral aphthous ulcers.
2. Genital ulcers.
3. Uveitis

General

Etiology:

• Unknown - hypothesized to be infectious due to the epidemiology.

Clinical

• Pathergy = minor trauma (to the skin) results in a non-healing lesion.

Microscopic

Features - small vessel vasculitis:

• Fibrinoid necrosis of the vessel walls.
• Inflammatory cells in the blood vessel walls.