Penis
The penis is occasionally afflicted by disease that the pathologist see.
It is afflicted by common skin pathologies.
Diseases
Inflammatory
- Phimosis.
- Paraphimosis.
- Balanoposthitis.
- Balanatis.
- Plasma cell balanitis.
- Balanitis xerotica obliterans.
- Balanitis circinata.
- Lipogranulomas.
Infectious
- HPV infection.
- HSV infection.
- Scabies.
- Pediculosis pubis.
- Syphilis.
- Gonorrhea.
- Lymphogranuloma venereum.
- Granuloma inguinale.
- Chancroid.
- Molluscum contagiosum.
- Filariasis - elephantiasis.
Other non-tumour
- Idiopathic scrotal calcinosis.
- Melanocytic lesions, esp. nevi.
Pre-cancerous
- Penile intraepithelial neoplasia (PIN).
- Paget disease (like extramammary Paget disease). (???)
Neoplastic
- Squamous cell carcinoma.
- Merkel cell carcinoma.
- Sebaceous carcinoma.
- Clear cell carcinoma.
- Basal cell carcinoma.
- Melanoma.
Others:
- Mesenchymal lesions - see: soft tissue lesions.
- Hematopoetic, e.g. lymphoma.
- Metastasis.
Specific conditions
Phimosis
General
- Cannot be retract foreskin.
- This is a clinical diagnosis.
Microscopic
Features:[1]
- +/-Inflammation.
- Fibrosis.
Notes: Findings non-specific.
DDx - general:
- Squamous cell carcinoma.
- Balanitis xerotica obliterans.
- Lichen planus.
- Infection, e.g. syphilis.
Penile fibromatosis
Main article: Fibromatosis
- AKA Peyronie's disease.
General
- Prevalence ~5%.[2]
Treatment:
- Conservative versus surgery.
Gross
- Abnormal curvature of the penis, esp. in the erect state.
Microscopic
Features:[2]
- Tunica albuginea fibrosis.
See also
References
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 391. ISBN 978-0781765275.
- ↑ 2.0 2.1 Serefoglu, EC.; Hellstrom, WJ. (Dec 2011). "Treatment of Peyronie's disease: 2012 update.". Curr Urol Rep 12 (6): 444-52. doi:10.1007/s11934-011-0212-2. PMID 21818660.