Mast cell
The mast cell is an uncommonly cell that occasionally causes problems.
Microscopic
Features:
- Ovoid/round cell with moderate amount of gray granular cytoplasm.
- Nuclear ovoid/round.
- No obvious nucleolus.
- May be more abundant around blood vessels.
Notes:
- Lymphocyte vs. mast cell:
- Lymphocytes = round; mast cells = ovoid.
Images:
- www:
- WC:
Diseases
- Mastocytosis.
- Urticaria pigmentosa.
- Asthma.[1]
Conditions associated with the presence of mast cells
Stains
- Giemsa stain.
- Tyrosinase.[3] (???)
IHC
- CD117 +ve.
References
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 370-2. ISBN 978-1416054542.
- ↑ Carr, NJ.; Warren, AY. (Jan 1993). "Mast cell numbers in melanocytic naevi and cutaneous neurofibromas.". J Clin Pathol 46 (1): 86-7. PMID 8432898.
- ↑ URL: http://www.nature.com/jid/journal/v53/n1/full/jid1969105a.html. Accessed on: 20 December 2011.