Radiation colitis

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Radiation colitis is inflammation of the colon due to radiation.

Microscopic

Features - acute:[1]

  • Mucosal changes:
    • Necrosis of epithelium.
      • "Ghost cells" = cells without nuclei.
    • Hemorrhage.
  • Submucosa edema with neutrophilic infiltrate.
  • +/-Fibrin thrombi.

Image:

See also

References

  1. ↑ 1.0 1.1 Yano, Y.; Yao, H.; Aoyagi, K.; Kawakubo, K.; Nakamura, S.; Doi, K.; Ibayashi, S.; Fujishima, M. (Sep 1997). "Photochemically induced colonic ischaemic lesions: a new model of ischaemic colitis in rats.". Gut 41 (3): 354-7. PMID 9378391.
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