Prostate chips grossing
Jump to navigation
Jump to search
This article deals with prostate chips.
Introduction
Prostate chips are generated from transurethral resection of the prostate (TURP) procedures. These are generally for relieving urinary obstruction due to nodular hyperplasia of the prostate (benign prostatic hyperplasia); however, urinary obstruction may be secondary to prostate cancer. Thus, the job of the pathologist here, usually, is excluding an incidental cancer.
The prevalence of prostate cancer is TURP specimens is approximately 17% based on a series of 747 specimens.[1]
Protocol
Specimen:
- Weight ___ grams.
- Dimensions (in aggregate): ___ x ___ x ___ cm.
- Number of fragments: [1-6 / multiple (>6)].
- Appearance: [tan-gray / yellow / orange].
- Consistency: [rubbery / firm].
- Other: [none / hemorrhagic appearance / necrotic appearing].
[Submitted in total/Representative sections submitted] in block(s) ___.
Protocol notes
Number of cassettes:[2]
- <= 12 grams: EIT.
- >12 grams: embed 12 grams and 1 cassette for every additional 5 grams.
- If the prostate chips have a mass of:
- 16 grams: 6-8 cassettes for 12 grams + 1 cassette = 7-9 cassettes.
- 21 grams: 6-8 cassettes for 12 grams + 2 cassettes = 7-9 cassettes.
- If the prostate chips have a mass of:
What to look for/feel for:[2]
| Entity | Colour | Firmness |
|---|---|---|
| Prostate cancer | yellow/orange | firm |
| Benign prostate | tan/gray | rubbery |
Alternate approaches
See also
Related protocols
References
- ↑ Trpkov, K.; Thompson, J.; Kulaga, A.; Yilmaz, A. (Aug 2008). "How much tissue sampling is required when unsuspected minimal prostate carcinoma is identified on transurethral resection?". Arch Pathol Lab Med 132 (8): 1313-6. doi:10.1043/1543-2165(2008)132[1313:HMTSIR]2.0.CO;2. PMID 18684032.
- ↑ 2.0 2.1 Lester, Susan Carole (2005). Manual of Surgical Pathology (2nd ed.). Saunders. pp. 398. ISBN 978-0443066450.