Estrogen receptor

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Estrogen receptor, abbreviated ER, is a common immunostain.

General

In the context of breast pathology it is a class II IHC test, as it is used for treatment decisions by itself.^[1]

Positive

Breast carcinoma - most.
- Ductal carcinoma in situ - most.
- Invasive lobular breast carcinoma - all.
- Invasive ductal carcinoma of breast - most.
Endometrial carcinomas.

Negative

Endocervical adenocarcinoma.

See also

Breast pathology.

References

↑ Torlakovic, EE.; Riddell, R.; Banerjee, D.; El-Zimaity, H.; Pilavdzic, D.; Dawe, P.; Magliocco, A.; Barnes, P. et al. (Mar 2010). "Canadian Association of Pathologists-Association canadienne des pathologistes National Standards Committee/Immunohistochemistry: best practice recommendations for standardization of immunohistochemistry tests.". Am J Clin Pathol 133 (3): 354-65. doi:10.1309/AJCPDYZ1XMF4HJWK. PMID 20154273.

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Immunohistochemistry