Mast cell

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The mast cell is an uncommonly cell that occasionally causes problems.

Morphology

Features:

  • Lymphocyte-like with more cytoplasm that is granular.
    • Cells may have spindled or stellate morphology.
    • Tend to be more abundant around vessels.

Notes:

  • Lymphocyte vs. mast cell:
    • Lymphocytes = round; mast cells = ovoid.

Diseases

Stains

IHC

  • CD117 +ve.

References

  1. ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 370-2. ISBN 978-1416054542.
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